Zachodniopomorski Uniwersytet Technologiczny w Szczecinie

Wydział Technologii i Inżynierii Chemicznej - Chemical Engineering (S1)

Sylabus przedmiotu Introduction to Pharmaceutical Engineering:

Informacje podstawowe

Kierunek studiów Chemical Engineering
Forma studiów studia stacjonarne Poziom pierwszego stopnia
Tytuł zawodowy absolwenta inżynier
Obszary studiów charakterystyki PRK, kompetencje inżynierskie PRK
Profil ogólnoakademicki
Moduł —
Przedmiot Introduction to Pharmaceutical Engineering
Specjalność przedmiot wspólny
Jednostka prowadząca Katedra Inżynierii Polimerów i Biomateriałów
Nauczyciel odpowiedzialny Piotr Sobolewski <psobolewski@zut.edu.pl>
Inni nauczyciele
ECTS (planowane) 6,0 ECTS (formy) 6,0
Forma zaliczenia egzamin Język angielski
Blok obieralny 8 Grupa obieralna 1

Formy dydaktyczne

Forma dydaktycznaKODSemestrGodzinyECTSWagaZaliczenie
wykładyW5 30 3,00,50egzamin
laboratoriaL5 45 3,00,50zaliczenie

Wymagania wstępne

KODWymaganie wstępne
W-1Introduction to chemistry

Cele przedmiotu

KODCel modułu/przedmiotu
C-1Define important keywords and concepts
C-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation

Treści programowe z podziałem na formy zajęć

KODTreść programowaGodziny
laboratoria
T-L-1Synthesis, purification & analysis of selected active compound15
T-L-2Drug formulation10
T-L-3Quality control of pharmaceutical product5
T-L-4Nanocarriers for drug delivery5
T-L-5Microspheres for Protein Delivery5
T-L-6Particulate drug carrier characterization5
45
wykłady
T-W-1Introduction: history, definitions and pharmaceutical industry2
T-W-2Drug discovery and development processes2
T-W-3Unit processes and operations in pharmaceutical engineering6
T-W-4Drug Formulations4
T-W-5Quality Control6
T-W-6Pharmacokinetics & Pharmacodynamics5
T-W-7Drug Delivery Systems5
30

Obciążenie pracą studenta - formy aktywności

KODForma aktywnościGodziny
laboratoria
A-L-1Participation in laboratory exercises45
A-L-2Preparing for labs (readings)10
A-L-3Preparing labs reports18
A-L-4Consultations2
75
wykłady
A-W-1Participation in lecture30
A-W-2Exam3
A-W-3Preparing for the exam20
A-W-4Preparing for class (readings)10
A-W-5Independent study10
A-W-6Consultations2
75

Metody nauczania / narzędzia dydaktyczne

KODMetoda nauczania / narzędzie dydaktyczne
M-1Laboratory Exercises
M-2Powerpoint and whiteboard lectures
M-3In-class discussion

Sposoby oceny

KODSposób oceny
S-1Ocena formująca: Evaluation of working in the laboratory
S-2Ocena podsumowująca: Evaluation of written reports
S-3Ocena podsumowująca: Exam

Zamierzone efekty uczenia się - wiedza

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
ChEn_1A_C27a_W01
Student will be able to describe the biological activity of selected medicines		ChEn_1A_W13, ChEn_1A_W15——C-1, C-2, C-3, C-4T-W-1, T-W-2, T-W-3, T-W-4, T-W-5, T-W-6, T-W-7M-1S-2
ChEn_1A_C27a_W02
Student will be able to characterize the synthesis methods of selected medicines		ChEn_1A_W13, ChEn_1A_W15——C-2, C-3, C-4T-W-2, T-W-3, T-W-4, T-W-6, T-L-1M-1S-2

Zamierzone efekty uczenia się - umiejętności

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
ChEn_1A_C27a_U01
Student will be able to perform the synthesis and analysis of selected medicines following the instruction		ChEn_1A_U01, ChEn_1A_U03, ChEn_1A_U05, ChEn_1A_U08, ChEn_1A_U16——C-2, C-3, C-4T-L-1, T-L-2, T-L-3, T-L-4, T-L-5M-1S-1
ChEn_1A_C27a_U02
Student will be able to collect and organize data from literature.		ChEn_1A_U01, ChEn_1A_U03, ChEn_1A_U05, ChEn_1A_U08, ChEn_1A_U16——C-2, C-3, C-4T-L-1, T-L-2, T-L-3, T-L-4, T-L-5M-1S-2

Zamierzone efekty uczenia się - inne kompetencje społeczne i personalne

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaOdniesienie do efektów uczenia się prowadzących do uzyskania tytułu zawodowego inżynieraCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
ChEn_1A_C27a_K01
Student will be aware of biological effects associated with the use of medicines		ChEn_1A_K01, ChEn_1A_K05——C-2, C-3, C-4T-W-2, T-W-3, T-W-4, T-W-5, T-W-6, T-W-7M-1S-2

Kryterium oceny - wiedza

Efekt uczenia sięOcenaKryterium oceny
ChEn_1A_C27a_W01
Student will be able to describe the biological activity of selected medicines		2,0
3,0Student is able to describe the basics of biological activity of selected medicines
3,5
4,0
4,5
5,0
ChEn_1A_C27a_W02
Student will be able to characterize the synthesis methods of selected medicines		2,0
3,0Student is able to describe the basic synthesis methods of selected medicines
3,5
4,0
4,5
5,0

Kryterium oceny - umiejętności

Efekt uczenia sięOcenaKryterium oceny
ChEn_1A_C27a_U01
Student will be able to perform the synthesis and analysis of selected medicines following the instruction		2,0
3,0Student is able to perform the synthesis and analysis of selected medicines following the instruction with help of the teacher
3,5
4,0
4,5
5,0
ChEn_1A_C27a_U02
Student will be able to collect and organize data from literature.		2,0
3,0student is able to prepare a report on a specified topic
3,5
4,0
4,5
5,0

Kryterium oceny - inne kompetencje społeczne i personalne

Efekt uczenia sięOcenaKryterium oceny
ChEn_1A_C27a_K01
Student will be aware of biological effects associated with the use of medicines		2,0
3,0Student is aware of biological effects associated with the use of medicines
3,5
4,0
4,5
5,0

Literatura podstawowa

  1. Lednicer D., The Organic Chemistry of Drug Synthesis, Wiley, New York, 1995
  2. Kleemann A., Engel J., Pharmaceutical Substances. Syntheses, Patents, Applications, Thieme, Stuttgard, 2001, 4th Ed.
  3. Gad S.C., Pharmaceutical Manufacturing Handbook. Production and Processes, John Wiley & Sons, Inc., New Jersey, 2008

Literatura dodatkowa

  1. Crist et al., Common pitfalls in nanotechnology: lessons learned from NCI’s Nanotechnology Characterization Laboratory, Integrative Biology, 2013, 5, 66, 10.1039/c2ib20117h
  2. Kim et al, Nanomedicine, NEJM, 2010, 363, 25, 2434, 10.1056/NEJMra0912273
  3. Furniss B.S., Hannaford A.J., Smith, P.W.G., Tatchell A.R., Vogel’s Textbook of Practical Organic chemistry, The School of Chemistry, Thames Polytechnic, London, 1989, 5th Ed.
  4. Joseph DiPiro, Introduction to Pharmacokinetics and Pharmacodynamics, ASHP, 2010, in: Concepts in Clinical Pharmacokinetics

Treści programowe - laboratoria

KODTreść programowaGodziny
T-L-1Synthesis, purification & analysis of selected active compound15
T-L-2Drug formulation10
T-L-3Quality control of pharmaceutical product5
T-L-4Nanocarriers for drug delivery5
T-L-5Microspheres for Protein Delivery5
T-L-6Particulate drug carrier characterization5
45

Treści programowe - wykłady

KODTreść programowaGodziny
T-W-1Introduction: history, definitions and pharmaceutical industry2
T-W-2Drug discovery and development processes2
T-W-3Unit processes and operations in pharmaceutical engineering6
T-W-4Drug Formulations4
T-W-5Quality Control6
T-W-6Pharmacokinetics & Pharmacodynamics5
T-W-7Drug Delivery Systems5
30

Formy aktywności - laboratoria

KODForma aktywnościGodziny
A-L-1Participation in laboratory exercises45
A-L-2Preparing for labs (readings)10
A-L-3Preparing labs reports18
A-L-4Consultations2
75
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta

Formy aktywności - wykłady

KODForma aktywnościGodziny
A-W-1Participation in lecture30
A-W-2Exam3
A-W-3Preparing for the exam20
A-W-4Preparing for class (readings)10
A-W-5Independent study10
A-W-6Consultations2
75
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C27a_W01Student will be able to describe the biological activity of selected medicines
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_W13Has knowledge of the current state and the latest developmental trends in chemical engineering and technology as well as the related areas in Poland and abroad.
ChEn_1A_W15Knows basic methods, techniques, tools and materials used for solving simple engineering tasks within the scope of chemical engineering and technology.
Cel przedmiotuC-1Define important keywords and concepts
C-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-W-1Introduction: history, definitions and pharmaceutical industry
T-W-2Drug discovery and development processes
T-W-3Unit processes and operations in pharmaceutical engineering
T-W-4Drug Formulations
T-W-5Quality Control
T-W-6Pharmacokinetics & Pharmacodynamics
T-W-7Drug Delivery Systems
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is able to describe the basics of biological activity of selected medicines
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C27a_W02Student will be able to characterize the synthesis methods of selected medicines
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_W13Has knowledge of the current state and the latest developmental trends in chemical engineering and technology as well as the related areas in Poland and abroad.
ChEn_1A_W15Knows basic methods, techniques, tools and materials used for solving simple engineering tasks within the scope of chemical engineering and technology.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-W-2Drug discovery and development processes
T-W-3Unit processes and operations in pharmaceutical engineering
T-W-4Drug Formulations
T-W-6Pharmacokinetics & Pharmacodynamics
T-L-1Synthesis, purification & analysis of selected active compound
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is able to describe the basic synthesis methods of selected medicines
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C27a_U01Student will be able to perform the synthesis and analysis of selected medicines following the instruction
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_U01Is able to obtain information from literature, data bases and other sources related to chemical engineering and technology as well as related areas; is able to integrate the obtained information, interpret it, draw proper conclusions and formulate opinions with their justification.
ChEn_1A_U03Is able to prepare, in English or another foreign language, a well-documented study of problems within the scope of chemical and process engineering; is able to develop documentation concerning the accomplishment of an engineering task.
ChEn_1A_U05Has the ability to learn, e.g. to raise professional competences.
ChEn_1A_U08Is able to plan and conduct process experiments, including measurements and computer simulations, as well as to interpret the obtained results and draw conclusions.
ChEn_1A_U16Is able to assess the usefulness of routine methods and tools used for solving a simple engineering task of practical nature characteristic for chemical engineering and technology as well as select and use a proper performance method and tools.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-L-1Synthesis, purification & analysis of selected active compound
T-L-2Drug formulation
T-L-3Quality control of pharmaceutical product
T-L-4Nanocarriers for drug delivery
T-L-5Microspheres for Protein Delivery
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-1Ocena formująca: Evaluation of working in the laboratory
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is able to perform the synthesis and analysis of selected medicines following the instruction with help of the teacher
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C27a_U02Student will be able to collect and organize data from literature.
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_U01Is able to obtain information from literature, data bases and other sources related to chemical engineering and technology as well as related areas; is able to integrate the obtained information, interpret it, draw proper conclusions and formulate opinions with their justification.
ChEn_1A_U03Is able to prepare, in English or another foreign language, a well-documented study of problems within the scope of chemical and process engineering; is able to develop documentation concerning the accomplishment of an engineering task.
ChEn_1A_U05Has the ability to learn, e.g. to raise professional competences.
ChEn_1A_U08Is able to plan and conduct process experiments, including measurements and computer simulations, as well as to interpret the obtained results and draw conclusions.
ChEn_1A_U16Is able to assess the usefulness of routine methods and tools used for solving a simple engineering task of practical nature characteristic for chemical engineering and technology as well as select and use a proper performance method and tools.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-L-1Synthesis, purification & analysis of selected active compound
T-L-2Drug formulation
T-L-3Quality control of pharmaceutical product
T-L-4Nanocarriers for drug delivery
T-L-5Microspheres for Protein Delivery
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0student is able to prepare a report on a specified topic
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięChEn_1A_C27a_K01Student will be aware of biological effects associated with the use of medicines
Odniesienie do efektów kształcenia dla kierunku studiówChEn_1A_K01Understands the need of learning and raising professional and personal competences, motivating other colleagues.
ChEn_1A_K05Is able to manage his/her own professional development, taking decisions and solving problems, including interpersonal ones connected with job performance.
Cel przedmiotuC-2Understand processes involved in drug development, from synthesis to formulation
C-3Describe the in vivo behavior and fate of a drug
C-4Discuss delivery-related design considerations of a drug formulation
Treści programoweT-W-2Drug discovery and development processes
T-W-3Unit processes and operations in pharmaceutical engineering
T-W-4Drug Formulations
T-W-5Quality Control
T-W-6Pharmacokinetics & Pharmacodynamics
T-W-7Drug Delivery Systems
Metody nauczaniaM-1Laboratory Exercises
Sposób ocenyS-2Ocena podsumowująca: Evaluation of written reports
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student is aware of biological effects associated with the use of medicines
3,5
4,0
4,5
5,0