Zachodniopomorski Uniwersytet Technologiczny w Szczecinie

Administracja Centralna Uczelni - Wymiana międzynarodowa (S1)

Sylabus przedmiotu Genomics:

Informacje podstawowe

Kierunek studiów Wymiana międzynarodowa
Forma studiów studia stacjonarne Poziom pierwszego stopnia
Tytuł zawodowy absolwenta
Obszary studiów
Profil
Moduł
Przedmiot Genomics
Specjalność przedmiot wspólny
Jednostka prowadząca Katedra Genetyki, Hodowli i Biotechnologii Roślin
Nauczyciel odpowiedzialny Paweł Milczarski <Pawel.Milczarski@zut.edu.pl>
Inni nauczyciele Beata Myśków <Beata.Myskow@zut.edu.pl>, Magdalena Pol-Szyszko <Magdalena.Pol-Szyszko@zut.edu.pl>, Miłosz Smolik <Milosz.Smolik@zut.edu.pl>, Stefan Stojałowski <Stefan.Stojalowski@zut.edu.pl>
ECTS (planowane) 6,0 ECTS (formy) 6,0
Forma zaliczenia zaliczenie Język angielski
Blok obieralny Grupa obieralna

Formy dydaktyczne

Forma dydaktycznaKODSemestrGodzinyECTSWagaZaliczenie
laboratoriaL1 40 4,00,40zaliczenie
wykładyW1 20 2,00,60zaliczenie

Wymagania wstępne

KODWymaganie wstępne
W-1Basic of genetics, molecular biology and plant breednig

Cele przedmiotu

KODCel modułu/przedmiotu
C-1Identification of differences in the structure of pro- and eukaryotic genomes. Knowledge on the methods of genome analyses.

Treści programowe z podziałem na formy zajęć

KODTreść programowaGodziny
laboratoria
T-L-1Genetic mapping, construction of genetic maps, data formats and their input into a computer program. Generation of maps and analysis of results8
T-L-2QTL mapping using the CIM interval method. Input data, its format and analysis. Other methods of QTL identification. Linkage disequilibrium8
T-L-3Sequence data analysis. Source data and their conversion to “fasta” format. Basic techniques for analyzing sequence data8
T-L-4Alignment of sequences obtained from NGS to a reference genome. Principles and programs used.8
T-L-5Phylogenetic analyses, types of comparisons, example genetic similarity trees.8
40
wykłady
T-W-1Introduction to Genomics: Definition and classification of genomes. Structural and functional genomics, and comparative. Origins and technical merits of Genomics. Biological databases, annotation system of genomes.4
T-W-2The procariotic genomes system. The bacterial chromosome. Prokaryotic genomes organization, pangenomes. Escherichia coli genome. Size and number of genes in prokaryotic genomes. Horizontal gene transfer. Metagenomics and its applications. Chloroplasts and mitochondria genomes4
T-W-3Eucariotic genomes. Organization of the eukaryotic genomes. Duplications in the genomes: mechanisms, types and consequence. Divergence between sequences and the molecular clock. Gene families and superfamilies. Genome rearrangement.4
T-W-4Genomes, transcriptomes, and proteomes. Mapping of genomes. Sequencing of genomes - sequencing technologies.4
T-W-5Genetic maps and physical maps of spouses. Methodological approaches to genome sequencing: Map-based (clone to clone) and shotgun at the genome level (whole genome shotgun, WGS). Considerations when sequencing genomes. De novo sequencing and resequencing. Natural selection and changes in haplotype frequency. Genome wide association studies (GWAS). Linkage disequilibrium.4
20

Obciążenie pracą studenta - formy aktywności

KODForma aktywnościGodziny
laboratoria
A-L-1presence at laboratory40
A-L-2preparation of the reports40
A-L-3preparing to pass laboratory pass20
100
wykłady
A-W-1presence of lecture20
A-W-2preparing to pass lecture10
A-W-3reading literature10
A-W-4homeworks and exam preparation10
50

Metody nauczania / narzędzia dydaktyczne

KODMetoda nauczania / narzędzie dydaktyczne
M-1Lecture
M-2Laboratory

Sposoby oceny

KODSposób oceny
S-1Ocena formująca: Practical exercise
S-2Ocena podsumowująca: Written exam

Zamierzone efekty uczenia się - wiedza

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
WM-WKSiR_1-_??_W01
The student has knowledge about the structure and changes within the genome
C-1T-W-1, T-W-5, T-W-3, T-W-2, T-W-4M-1S-2

Zamierzone efekty uczenia się - umiejętności

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
WM-WKSiR_1-_??_U01
The student has the skills to analyze the genome using bioinformatics tools.
C-1T-L-4, T-L-3, T-L-1, T-L-5, T-L-2M-2S-1

Zamierzone efekty uczenia się - inne kompetencje społeczne i personalne

Zamierzone efekty uczenia sięOdniesienie do efektów kształcenia dla kierunku studiówOdniesienie do efektów zdefiniowanych dla obszaru kształceniaCel przedmiotuTreści programoweMetody nauczaniaSposób oceny
WM-WKSiR_1-_??_K01
The student is able to work in a group and obtain data from various sources.
C-1T-L-1, T-W-4, T-W-2, T-W-3, T-L-4, T-L-5, T-W-1, T-L-2, T-W-5, T-L-3M-2S-1

Kryterium oceny - wiedza

Efekt uczenia sięOcenaKryterium oceny
WM-WKSiR_1-_??_W01
The student has knowledge about the structure and changes within the genome
2,0
3,0The student knows the basic principles of the structure and functioning of the genome.
3,5
4,0
4,5
5,0

Kryterium oceny - umiejętności

Efekt uczenia sięOcenaKryterium oceny
WM-WKSiR_1-_??_U01
The student has the skills to analyze the genome using bioinformatics tools.
2,0
3,0The student is able to use the basic programs used in sequence analysis.
3,5
4,0
4,5
5,0

Kryterium oceny - inne kompetencje społeczne i personalne

Efekt uczenia sięOcenaKryterium oceny
WM-WKSiR_1-_??_K01
The student is able to work in a group and obtain data from various sources.
2,0
3,0Student has acquired the competence to work in groups, he understands the need for training
3,5
4,0
4,5
5,0

Literatura podstawowa

  1. T.A. Brown, Genomes, Garland Science Publishing, 2019, II

Treści programowe - laboratoria

KODTreść programowaGodziny
T-L-1Genetic mapping, construction of genetic maps, data formats and their input into a computer program. Generation of maps and analysis of results8
T-L-2QTL mapping using the CIM interval method. Input data, its format and analysis. Other methods of QTL identification. Linkage disequilibrium8
T-L-3Sequence data analysis. Source data and their conversion to “fasta” format. Basic techniques for analyzing sequence data8
T-L-4Alignment of sequences obtained from NGS to a reference genome. Principles and programs used.8
T-L-5Phylogenetic analyses, types of comparisons, example genetic similarity trees.8
40

Treści programowe - wykłady

KODTreść programowaGodziny
T-W-1Introduction to Genomics: Definition and classification of genomes. Structural and functional genomics, and comparative. Origins and technical merits of Genomics. Biological databases, annotation system of genomes.4
T-W-2The procariotic genomes system. The bacterial chromosome. Prokaryotic genomes organization, pangenomes. Escherichia coli genome. Size and number of genes in prokaryotic genomes. Horizontal gene transfer. Metagenomics and its applications. Chloroplasts and mitochondria genomes4
T-W-3Eucariotic genomes. Organization of the eukaryotic genomes. Duplications in the genomes: mechanisms, types and consequence. Divergence between sequences and the molecular clock. Gene families and superfamilies. Genome rearrangement.4
T-W-4Genomes, transcriptomes, and proteomes. Mapping of genomes. Sequencing of genomes - sequencing technologies.4
T-W-5Genetic maps and physical maps of spouses. Methodological approaches to genome sequencing: Map-based (clone to clone) and shotgun at the genome level (whole genome shotgun, WGS). Considerations when sequencing genomes. De novo sequencing and resequencing. Natural selection and changes in haplotype frequency. Genome wide association studies (GWAS). Linkage disequilibrium.4
20

Formy aktywności - laboratoria

KODForma aktywnościGodziny
A-L-1presence at laboratory40
A-L-2preparation of the reports40
A-L-3preparing to pass laboratory pass20
100
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta

Formy aktywności - wykłady

KODForma aktywnościGodziny
A-W-1presence of lecture20
A-W-2preparing to pass lecture10
A-W-3reading literature10
A-W-4homeworks and exam preparation10
50
(*) 1 punkt ECTS, odpowiada około 30 godzinom aktywności studenta
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięWM-WKSiR_1-_??_W01The student has knowledge about the structure and changes within the genome
Cel przedmiotuC-1Identification of differences in the structure of pro- and eukaryotic genomes. Knowledge on the methods of genome analyses.
Treści programoweT-W-1Introduction to Genomics: Definition and classification of genomes. Structural and functional genomics, and comparative. Origins and technical merits of Genomics. Biological databases, annotation system of genomes.
T-W-5Genetic maps and physical maps of spouses. Methodological approaches to genome sequencing: Map-based (clone to clone) and shotgun at the genome level (whole genome shotgun, WGS). Considerations when sequencing genomes. De novo sequencing and resequencing. Natural selection and changes in haplotype frequency. Genome wide association studies (GWAS). Linkage disequilibrium.
T-W-3Eucariotic genomes. Organization of the eukaryotic genomes. Duplications in the genomes: mechanisms, types and consequence. Divergence between sequences and the molecular clock. Gene families and superfamilies. Genome rearrangement.
T-W-2The procariotic genomes system. The bacterial chromosome. Prokaryotic genomes organization, pangenomes. Escherichia coli genome. Size and number of genes in prokaryotic genomes. Horizontal gene transfer. Metagenomics and its applications. Chloroplasts and mitochondria genomes
T-W-4Genomes, transcriptomes, and proteomes. Mapping of genomes. Sequencing of genomes - sequencing technologies.
Metody nauczaniaM-1Lecture
Sposób ocenyS-2Ocena podsumowująca: Written exam
Kryteria ocenyOcenaKryterium oceny
2,0
3,0The student knows the basic principles of the structure and functioning of the genome.
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięWM-WKSiR_1-_??_U01The student has the skills to analyze the genome using bioinformatics tools.
Cel przedmiotuC-1Identification of differences in the structure of pro- and eukaryotic genomes. Knowledge on the methods of genome analyses.
Treści programoweT-L-4Alignment of sequences obtained from NGS to a reference genome. Principles and programs used.
T-L-3Sequence data analysis. Source data and their conversion to “fasta” format. Basic techniques for analyzing sequence data
T-L-1Genetic mapping, construction of genetic maps, data formats and their input into a computer program. Generation of maps and analysis of results
T-L-5Phylogenetic analyses, types of comparisons, example genetic similarity trees.
T-L-2QTL mapping using the CIM interval method. Input data, its format and analysis. Other methods of QTL identification. Linkage disequilibrium
Metody nauczaniaM-2Laboratory
Sposób ocenyS-1Ocena formująca: Practical exercise
Kryteria ocenyOcenaKryterium oceny
2,0
3,0The student is able to use the basic programs used in sequence analysis.
3,5
4,0
4,5
5,0
PoleKODZnaczenie kodu
Zamierzone efekty uczenia sięWM-WKSiR_1-_??_K01The student is able to work in a group and obtain data from various sources.
Cel przedmiotuC-1Identification of differences in the structure of pro- and eukaryotic genomes. Knowledge on the methods of genome analyses.
Treści programoweT-L-1Genetic mapping, construction of genetic maps, data formats and their input into a computer program. Generation of maps and analysis of results
T-W-4Genomes, transcriptomes, and proteomes. Mapping of genomes. Sequencing of genomes - sequencing technologies.
T-W-2The procariotic genomes system. The bacterial chromosome. Prokaryotic genomes organization, pangenomes. Escherichia coli genome. Size and number of genes in prokaryotic genomes. Horizontal gene transfer. Metagenomics and its applications. Chloroplasts and mitochondria genomes
T-W-3Eucariotic genomes. Organization of the eukaryotic genomes. Duplications in the genomes: mechanisms, types and consequence. Divergence between sequences and the molecular clock. Gene families and superfamilies. Genome rearrangement.
T-L-4Alignment of sequences obtained from NGS to a reference genome. Principles and programs used.
T-L-5Phylogenetic analyses, types of comparisons, example genetic similarity trees.
T-W-1Introduction to Genomics: Definition and classification of genomes. Structural and functional genomics, and comparative. Origins and technical merits of Genomics. Biological databases, annotation system of genomes.
T-L-2QTL mapping using the CIM interval method. Input data, its format and analysis. Other methods of QTL identification. Linkage disequilibrium
T-W-5Genetic maps and physical maps of spouses. Methodological approaches to genome sequencing: Map-based (clone to clone) and shotgun at the genome level (whole genome shotgun, WGS). Considerations when sequencing genomes. De novo sequencing and resequencing. Natural selection and changes in haplotype frequency. Genome wide association studies (GWAS). Linkage disequilibrium.
T-L-3Sequence data analysis. Source data and their conversion to “fasta” format. Basic techniques for analyzing sequence data
Metody nauczaniaM-2Laboratory
Sposób ocenyS-1Ocena formująca: Practical exercise
Kryteria ocenyOcenaKryterium oceny
2,0
3,0Student has acquired the competence to work in groups, he understands the need for training
3,5
4,0
4,5
5,0